Trump signs order to boost domestic drug manufacturing as pharma tariff threat looms 

President Donald Trump on Monday signed an executive order to incentivize drug manufacturing in the U.S., streamlining the path for pharmaceutical companies to build new production sites stateside. 

The order comes ahead of Trump’s planned tariffs on pharmaceuticals imported into the U.S. Those potential levies – and efforts to build goodwill with the President – have already fueled a fresh wave of domestic manufacturing investments from drugmakers such as Eli Lilly, Johnson & Johnson and AbbVie. 

It’s unclear when Trump could announce pharmaceutical-specific tariffs, or if the new executive order changes those plans. But the Trump administration disclosed in April that it had opened a so-called Section 232 investigation into how importing certain pharmaceuticals affects national security — a move widely seen as a prelude to initiating tariffs on drugs. 

Some pharmaceutical companies are starting to push back on Trump’s plans. For example, Pfizer CEO Albert Bourla said last week that the tariff threat is deterring the company from making further U.S. investments in research and development and manufacturing.

U.S. manufacturing in the pharmaceutical industry has shrunk significantly in recent decades. Production of most of the so-called active ingredients in medicines has moved to China and other countries, largely due to lower costs for labor and other parts of the process, according to the Food and Drug Administration.

The U.S. imported $203 billion in pharmaceutical products in 2023 alone, with 73% coming from Europe, primarily Ireland, Germany and Switzerland, according to analysis conducted by consulting firm EY. 

Reshoring manufacturing can help make the drug supply chain more robust, decreasing the risk of disruptions, according to an April release from GlobalData, a data and analytics company. Still, it could elevate production costs and drug prices, raising affordability concerns, GlobalData said.